ABCA1 Rabbit Polyclonal Antibody (CAB7228)
- SKU:
- CAB7228
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ABCA1 Rabbit Polyclonal Antibody |
SKU: | CAB7228 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2). |
Sequence: | IQYR FFIR PRPV NAKL SPLN DEDE DVRR ERQR ILDG GGQN DILE IKEL TKIY RRKR KPAV DRIC VGIP PGEC FGLL GVNG AGKS STFK MLTG DTTV TRGD AFLN KNSI LSNI HEVH QNMG YCPQ FDAI TELL TGRE HVEF FALL RGVP EKEV GKVG EWAI RKLG LVKY GEKY AGNY SGGN KRKL STAM ALIG GPPV VFLD EPTT GMDP KARR FLWN CALS VVKE GRSV VLTS HSME ECEA LCTR MAIM VNG |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13; ABCA1 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 254kDa |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.
Purification Method: | Affinity purification |
Gene ID: | 19 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |