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Anti-AARS2 Antibody (CAB7826)

SKU:
CAB7826
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 2 Anti-AARS2 Antibody CAB7826
  • Metabolism Antibodies 2 Anti-AARS2 Antibody CAB7826
€139 - €419
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Description

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Antibody Name:Anti-AARS2 Antibody
Antibody SKU:CAB7826
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 841-985 of human AARS2 (NP_065796.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human
Positive Samples:HepG2, SKOV3, U-251MG, MCF7
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 841-985 of human AARS2 (NP_065796.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RREL LATV KMLQ RRAN TAIR KLQM GQAA KKTQ ELLE RHSK GPLI VDTV SAES LSVL VKVV RQLC EQAP STSV LLLS PQPM GKVL CACQ VAQG AMPT FTAE AWAL AVCS HMGG KAWG SRVV AQGT GSTT DLEA ALSI AQTY ALSQ L
Gene ID:57505
Uniprot:Q5JTZ9
Cellular Location:Mitochondrion
Calculated MW:107kDa
Observed MW:107kDa
Synonyms:AARS2, AARSL, COXPD8, LKENP, MT-ALARS, MTALARS
Background:The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
NCBI Summary:The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]
UniProt Code:Q5JTZ9
NCBI GenInfo Identifier:38569417
NCBI Gene ID:57505
NCBI Accession:NP_065796.1
UniProt Related Accession:Q5JTZ9
Molecular Weight:108 kDa
NCBI Full Name:alanine--tRNA ligase, mitochondrial
NCBI Synonym Full Names:alanyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol:AARS2  
NCBI Official Synonym Symbols:AARSL; LKENP; COXPD8; MTALARS; MT-ALARS  
NCBI Protein Information:alanine--tRNA ligase, mitochondrial
UniProt Protein Name:Alanine--tRNA ligase, mitochondrial
UniProt Synonym Protein Names:Alanyl-tRNA synthetase; AlaRS
UniProt Gene Name:AARS2  
UniProt Entry Name:SYAM_HUMAN
Anti-AARS2 Antibody (CAB7826)Western blot analysis of extracts of various cell lines, using AARS2 antibody (CAB7826) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s.
Anti-AARS2 Antibody (CAB7826)Immunohistochemistry of paraffin-embedded human liver damage using AARS2 antibody (CAB7826) at dilution of 1:100 (40x lens).

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