The AAGAB Polyclonal Antibody (PACO54134) is a valuable tool for researchers investigating AAGAB, a protein involved in lipid metabolism and cell growth. This antibody is raised in rabbits and has been validated for use in various applications, including Western blotting and immunofluorescence.AAGAB plays a key role in the regulation of intracellular lipid transport and metabolism, making it an intriguing target for studies related to obesity, metabolic disorders, and cancer. By using the AAGAB Polyclonal Antibody, researchers can detect and analyze AAGAB expression in different cell types, providing valuable insights into its function and potential implications in disease pathology.
Overall, this antibody is a valuable asset for scientists conducting research in the fields of lipid metabolism, cell biology, and metabolic diseases. The accurate and reliable detection of AAGAB facilitated by this antibody can lead to a better understanding of its role in various physiological and pathological processes, paving the way for the development of targeted therapies and interventions.
Immunohistochemistry of paraffin-embedded human spleen tissue using PACO54134 at dilution of 1:100.
Immunofluorescent analysis of A549 cells using PACO54134 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO54134 at dilution of 1:100.
Background:
May be involved in endocytic recycling of growth factor receptors such as EGFR.
Synonyms:
Alpha- and gamma-adaptin-binding protein p34, AAGAB
UniProt Protein Function:
May be involved in endocytic recycling of growth factor receptors such as EGFR.
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
