The AADAC Polyclonal Antibody (CAB13936) is a valuable tool for researchers studying AADAC, an enzyme involved in drug metabolism and detoxification processes in the liver and other tissues. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting AADAC in human samples, making it suitable for Western blot analysis.AADAC, also known as arylacetamide deacetylase, plays a crucial role in the breakdown of various drugs and environmental toxins, influencing their efficacy and toxicity in the body. Researchers in pharmacology, toxicology, and drug development can benefit from utilizing this antibody to investigate the expression and function of AADAC in different biological contexts.
The AADAC Polyclonal Antibody offers a reliable tool for exploring the role of this enzyme in drug metabolism pathways, understanding its involvement in drug interactions and potential implications for personalized medicine approaches. By characterizing AADAC activity, researchers can enhance their knowledge of drug metabolism processes and develop strategies to optimize therapeutic interventions.
Product Name:
AADAC Rabbit Polyclonal Antibody
SKU:
CAB13936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-399 of human AADAC (NP_001077.2).
Endoplasmic reticulum membrane, Microsome membrane, Single-pass type II membrane protein.
Calculated MW:
46kDa
Observed MW:
46kDa
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens
Purification Method:
Affinity purification
Gene ID:
13
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AADAC antibody (CAB13936) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
