The AADAC Polyclonal Antibody (CAB10365) is a valuable tool for researchers studying the AADAC protein, a key enzyme involved in drug metabolism and detoxification processes in the body. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the AADAC protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in pharmacology, toxicology, and drug development.
AADAC, also known as arylacetamide deacetylase, plays a crucial role in the breakdown of various drugs and xenobiotic compounds in the liver and other tissues. Its involvement in drug metabolism pathways makes it a target of interest in understanding drug interactions, toxicity, and personalized medicine approaches. Research into AADAC function is essential for advancing our knowledge of how the body processes and responds to pharmaceutical agents, ultimately leading to improved drug safety and efficacy.
Product Name:
AADAC Rabbit Polyclonal Antibody
SKU:
CAB10365
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-399 of human AADAC (NP_001077.2).
Endoplasmic reticulum membrane, Microsome membrane, Single-pass type II membrane protein.
Calculated MW:
46kDa
Observed MW:
46kDa
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens
Purification Method:
Affinity purification
Gene ID:
13
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AADAC antibody (CAB10365) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
