The A4GNT Polyclonal Antibody (CAB12366) is a valuable tool for researchers studying the A4GNT protein, a glycosyltransferase enzyme involved in glycosylation processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for use in various research applications, including Western blotting. By targeting the A4GNT protein, this antibody enables the detection and analysis of A4GNT expression levels in different cell types, providing insights into its role in glycosylation pathways.
A4GNT is known to play a crucial role in the biosynthesis of various glycoproteins and glycolipids, influencing cell-cell interactions and signaling processes. Dysregulation of A4GNT expression has been linked to pathological conditions, including cancer and inflammatory disorders, making it a promising target for therapeutic interventions. Investigating the function of A4GNT using this polyclonal antibody can enhance our understanding of its involvement in disease progression and potentially lead to the development of novel treatments.
Product Name:
A4GNT Rabbit Polyclonal Antibody
SKU:
CAB12366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
39kDa
Observed MW:
37kDa
This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane.
Purification Method:
Affinity purification
Gene ID:
51146
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using A4GNT Rabbit pAb (CAB12366) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.