A2ML1 Rabbit Polyclonal Antibody (CAB17831)
- SKU:
- CAB17831
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | A2ML1 Rabbit Polyclonal Antibody |
SKU: | CAB17831 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human A2ML1 (NP_653271.3). |
Sequence: | PFTL ETSG WNGT DVSL EGKF QMED LVYN PEQV PRYY QNAY LHLR PFYS TTRS FLGI HRLN GPLK CGQP QEVL VDYY IDPA DASP DQEI SFSY YLIG KGSL V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OMS; p170; CPAMD9; A2ML1 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular exosome, extracellular space |
Calculated MW: | 161kDa |
Observed MW: | 161kDa |
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 144568 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |