2'-O-methylcytidine/ Cm Monoclonal Antibody (CAB20693)
The 2'-O-Methylcytidine (CM) Monoclonal Antibody is a powerful tool for researchers studying RNA modifications and their impact on gene expression. This antibody specifically targets 2'-O-Methylcytidine (CM), a common modification found in various RNA molecules. By binding to CM, this antibody allows for the detection and analysis of CM-modified RNA in a variety of cell types and tissues.RNA modifications, such as 2'-O-Methylcytidine, play a crucial role in regulating gene expression and can impact various cellular processes. Research into RNA modifications has shown their importance in gene regulation, RNA stability, and protein translation.
The 2'-O-Methylcytidine Monoclonal Antibody is a valuable tool for researchers aiming to understand the functional significance of RNA modifications and their role in disease processes.This antibody is raised in mice and has been extensively validated for use in techniques such as immunohistochemistry, immunofluorescence, and RNA immunoprecipitation. Its high specificity and sensitivity make it an ideal choice for studies investigating RNA modification patterns in different biological contexts. Researchers focusing on RNA biology, epigenetics, and gene regulation will find this antibody indispensable for their research efforts.
Product Name:
2'-O-methylcytidine/ Cm Monoclonal Antibody
SKU:
CAB20693
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Species independent
Immunogen:
Cm
Sequence:
Cm c onju gate d to KLH
Tested Applications:
ELISADB
Recommended Dilution:
DB,1:500 - 1:2000
Synonyms:
Cm; 2'-O-methylcytidine; 2'-O-methylcytidine/ Cm
Conjugate:
Unconjugated
Observed MW:
Refer to figures
RNA methylation plays a significant regulatory role in various of physiological activities. 2'-O-methylcytidine (Cm) is one of the representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2'-oxygen position. 2’-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2'-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2’-O-methylcytidine was involved in plant stress responses.
Purification Method:
Affinity purification
Clone Number:
ARC50639
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
The 2'-O-methylcytidine(Cm) Rabbit mAb (CAB20693) are tested in Dot Blot against 2'-O-methylcytidine and unmodified cytidine.2'-O-methylcytidine ：Biotin-5'CGATAACCACTAGT(Cm)3'unmodified cytosine：Biotin-5'CGATAACCACTAGTC3'
