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2-hydroxyisobutyryl-HIST1H2BC (K57) Antibody (PACO65046)

SKU:
PACO65046
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

2-hydroxyisobutyryl-HIST1H2BC (K57) Antibody (PACO65046)

The 2-Hydroxyisobutyryl-HIST1H2BC-K57 Antibody (PAC065046) is a polyclonal antibody designed for research involving the histone variant HIST1H2BC-K57, a key player in epigenetic regulation. The antibody, raised in rabbits, is highly specific and reactive with human samples, and has been validated for use in various applications such as Western blotting and immunofluorescence.HIST1H2BC-K57 is a histone variant that plays a crucial role in chromatin structure and gene expression regulation. Its modification with 2-hydroxyisobutyryl has been linked to gene activation and transcriptional regulation.

Understanding the role and function of this histone variant is essential for research in epigenetics, cancer biology, and developmental biology.This antibody enables the detection and analysis of 2-Hydroxyisobutyryl-HIST1H2BC-K57 in various cell types and tissues, allowing researchers to further explore its role in gene regulation and epigenetic modifications. Its high specificity and sensitivity make it a valuable tool for studies aiming to unravel the complex mechanisms of epigenetic regulation in health and disease.

Product Name:2-hydroxyisobutyryl-HIST1H2BC (K57) Antibody
Product Code:PACO65046
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (53-64aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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