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2-hydroxyisobutyryl-HIST1H2BC (K108) Antibody (PACO65130)

SKU:
PACO65130
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

2-hydroxyisobutyryl-HIST1H2BC (K108) Antibody (PACO65130)

The 2-Hydroxyisobutyryl-HIST1H2BC (K108) Antibody (PAC065130) is a specialized research tool designed for the study of histone modification processes. This antibody, produced through immunization of rabbits, is highly specific to the 2-hydroxyisobutyryl-HIST1H2BC (K108) protein and has been validated for use in techniques such as Western blotting.Histone modifications play a crucial role in regulating gene expression and chromatin structure, making them key players in various cellular processes such as DNA repair, replication, and transcription.

The detection and analysis of 2-hydroxyisobutyryl-HIST1H2BC (K108) using this antibody allows for deeper insights into the mechanisms underlying these biological functions.Researchers studying epigenetics, chromatin remodeling, or DNA packaging will find this antibody essential for their investigations. By understanding the role of 2-hydroxyisobutyryl-HIST1H2BC (K108) in these processes, new avenues for therapeutic interventions in diseases related to aberrant histone modifications may be uncovered.

Product Name:2-hydroxyisobutyryl-HIST1H2BC (K108) Antibody
Product Code:PACO65130
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (104-115aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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