The 14-3-3 Theta Rabbit Monoclonal Antibody (CAB8936) is a valuable tool for researchers studying the 14-3-3 Theta protein, a crucial signaling molecule involved in various cellular processes. This antibody, developed from rabbit monoclonal sources, demonstrates high specificity and sensitivity in detecting human samples through Western blot analysis.The 14-3-3 Theta protein plays a significant role in cell cycle regulation, apoptosis, and intracellular signaling pathways. Dysregulation of this protein has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. By targeting the 14-3-3 Theta protein with this antibody, researchers can gain insight into its functions and mechanisms in different cell types, aiding in further studies in molecular biology and disease pathology.
With its highly reactive nature and validated performance, the 14-3-3 Theta Rabbit Monoclonal Antibody (CAB8936) is a reliable tool for researchers conducting investigations in the fields of cell biology, cancer research, and neurology. Its ability to specifically bind to the 14-3-3 Theta protein opens up opportunities for understanding its role in disease progression and developing targeted therapies in the future.
Product Name:
14-3-3 Theta Rabbit Monoclonal Antibody
SKU:
CAB8936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 Theta (P27348).
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Purification Method:
Affinity purification
Gene ID:
10971
Clone Number:
ARC1358
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using 14-3-3 Theta Rabbit mAb (CAB8936) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
