The 14-3-3 Sigma Rabbit Monoclonal Antibody (CAB4377) is a powerful tool for researchers studying the 14-3-3 Sigma protein, a key player in cellular signaling pathways. This antibody, produced in rabbits, is highly specific and sensitive for detecting 14-3-3 Sigma in human samples, making it an excellent choice for Western blot applications.14-3-3 Sigma is involved in various cellular processes such as cell cycle regulation, apoptosis, and cell adhesion. Dysregulation of 14-3-3 Sigma has been linked to cancer development and progression, making it a promising target for cancer research.
By using the 14-3-3 Sigma Rabbit Monoclonal Antibody, researchers can accurately detect and measure levels of 14-3-3 Sigma in different cell types, providing valuable insights into its functions and potential therapeutic applications. This antibody is a valuable tool for studying the role of 14-3-3 Sigma in cancer biology and other diseases, ultimately contributing to the development of new treatment strategies.
Product Name:
14-3-3 sigma Rabbit Monoclonal Antibody
SKU:
CAB4377
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 sigma (P31947).
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.
Purification Method:
Affinity purification
Gene ID:
2810
Clone Number:
ARC0988
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using 14-3-3 sigma Rabbit mAb (CAB4377) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
