The 14-3-3 Gamma Rabbit Monoclonal Antibody (CAB9162) is a valuable tool for researchers studying the 14-3-3 gamma protein, a member of the 14-3-3 family of proteins known to be involved in a variety of cellular processes such as signal transduction, cell cycle control, and apoptosis. This antibody, produced in rabbits, has high specificity and sensitivity for detecting 14-3-3 gamma in human samples, making it suitable for use in Western blot applications.The 14-3-3 gamma protein is important for regulating diverse cellular functions, making it a key target for research in areas such as cancer, neurodegenerative diseases, and cardiovascular disorders.
Understanding the role of 14-3-3 gamma can provide insights into disease mechanisms and potential therapeutic strategies.By utilizing the 14-3-3 Gamma Rabbit Monoclonal Antibody (CAB9162), researchers can effectively detect and analyze the expression of 14-3-3 gamma in various cell types, aiding in the advancement of immunology, cancer research, and other fields where the protein plays a significant role.
Product Name:
14-3-3 gamma Rabbit Monoclonal Antibody
SKU:
CAB9162
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human 14-3-3 gamma (P61981).
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Purification Method:
Affinity purification
Gene ID:
7532
Clone Number:
ARC1457
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using 14-3-3 gamma Rabbit mAb (CAB9162) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
