14-3-3 epsilon Rabbit Monoclonal Antibody (CAB4933)
- SKU:
- CAB4933
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 14-3-3E
- HEL2
- KCIP-1
- MDCR
- MDS
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | 14-3-3 epsilon Rabbit Monoclonal Antibody |
SKU: | CAB4933 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 epsilon (P62258). |
Sequence: | MDDR EDLV YQAK LAEQ AERY DEMV ESMK KVAG MDVE LTVE ERNL LSVA YKNV IGAR RASW RIIS SIEQ KEEN KGGE DKLK MIRE YRQM VETE LKLI CCDI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MDS; HEL2; MDCR; KCIP-1; 14-3-3E; 14-3-3 epsilon |
Positive Sample: | HeLa,Mouse brain,Mouse kidney,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Melanosome. |
Calculated MW: | 29kDa |
Observed MW: | 28kDa |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7531 |
Clone Number: | ARC1222 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |